Inferring gene regulatory network

inferCSN

inferCSN-package

inferCSN: Inferring Cell-Specific Gene Regulatory Network

inferCSN()

Inferring Cell-Specific Gene Regulatory Network

Network processing

network_sift()

network_sift

Network evaluation

calculate_auc()

Calculate auc

calculate_acc()

Calculate acc

prepare_network_data()

Prepare network data

Network visualization

plot_dynamic_networks()

plot_dynamic_networks

plot_static_networks()

Plot of dynamic networks

plot_contrast_networks()

plot_contrast_networks

plot_network_heatmap()

The heatmap of network

Plotting functions

plot_scatter()

plot_scatter

plot_embedding()

plot_embedding

plot_weight_distribution()

plot_weight_distribution

Calculate gene rank

calculate_gene_rank()

Rank TFs and genes in network

Sparse regression model

single_network()

Construct network for single gene

sparse_regression()

Sparse regression model

fit_sparse_regression()

Fit a sparse regression model

Utils functions

as_matrix()

Convert dgCMatrix into a dense matrix

check_parameters()

Check input parameters

check_sparsity()

Check sparsity of matrix

coef(<SRM_fit>) coef(<SRM_fit_CV>)

Extracts a specific solution in the regularization path

network_format()

Format weight table

table_to_matrix()

Switch weight table to matrix

filter_sort_matrix()

Filter and sort matrix

normalization()

Normalize numeric vector

parallelize_fun()

Apply function over a List or Vector

print(<SRM_fit>) print(<SRM_fit_CV>)

Prints a summary of fit_sparse_regression

predict(<SRM_fit>) predict(<SRM_fit_CV>)

Predict Response

r_square()

\(R^2\) (coefficient of determination)

rse()

Relative Squared Error

sse()

Sum of Squared Errors

Example data

example_matrix

Example matrix data

example_meta_data

Example meta data

example_ground_truth

Example ground truth data