Gene signatures and common-gene universe used by RunESTIMATE() to compute
stromal, immune, combined ESTIMATE, and tumor-purity scores without requiring
the external estimate package.
Format
A list with five entries:
- stromal_signature
Character vector of stromal signature genes.
- immune_signature
Character vector of immune signature genes.
- common_genes
Character vector of common genes used for filtering.
- common_gene_aliases
Data frame mapping common gene symbols to aliases.
- source
List with source method, source data, and DOI metadata.
Source
Derived from tidyestimate 1.1.1 CRAN data files, which are derived from the
MD Anderson ESTIMATE implementation. The scoring references are
Yoshihara et al. (2013) and
Barbie et al. (2009).
Examples
data(estimate_signatures)
names(estimate_signatures)
#> [1] "stromal_signature" "immune_signature" "common_genes"
#> [4] "common_gene_aliases" "source"
lengths(estimate_signatures[c("stromal_signature", "immune_signature", "common_genes")])
#> stromal_signature immune_signature common_genes
#> 141 141 10391