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Apply SCTransform normalization

Usage

SCTransform(object, ...)

Arguments

object

Object containing count data.

...

Passed to methods.

Value

An object with SCTransform results.

Details

Calls that stick to the scop fast path defaults (vst.flavor = "v2", no conserve.memory) run through scop's optimized sparse implementation. Regression variables passed via vars.to.regress or latent.data are removed from the centered residuals with an ordinary least-squares fit on the fast path, matching Seurat's post-VST regression semantics. Truly unsupported combinations, such as conserve.memory, reference.SCT.model, residual.features, or vst.flavor = "v1", automatically delegate to the original Seurat::SCTransform implementation.